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Beyond the Mic: Exploring the Journeys of Leaders.

Cholestatic Pruritus Across the Age Spectrum: What Are You Missing?

When considering cholestatic pruritus across the age spectrum, a key point to remember is that while the underlying mechanism is similar, pediatric patients often present with unique challenges in diagnosis and management due to factors like limited communication abilities, potential side effects of medications, and the need for careful dosage adjustments; additionally, older adults might have co-morbidities that complicate treatment and require a more nuanced approach to managing pruritus

Publications

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Diagnosis and Management of Hepatitis Delta Virus Infection

Hepatitis D virus (HDV) depends on hepatitis B virus (HBV) to enter and exit hepatocytes and to replicate. Despite this dependency, HDV can cause severe liver disease. HDV accelerates liver fibrosis, increases the risk of hepatocellular carcinoma, and hastens hepatic decompensation compared to chronic HBV monoinfection. The Chronic Liver Disease Foundation (CLDF) formed an expert panel to publish updated guidelines on the testing, diagnosis, and management of hepatitis delta virus. The panel group performed network data review on the transmission, epidemiology, natural history, and disease sequelae of acute and chronic HDV infection. Based on current available evidence, we provide recommendations for screening, testing, diagnosis, and treatment of hepatitis D infection and review upcoming novel agents that may expand treatment options. The CLDF recommends universal HDV screening for all patients who are Hepatitis B surface antigen-positive. Initial screening should be with an assay to detect antibodies generated against HDV (anti-HDV). Patients who are positive for anti-HDV IgG antibodies should then undergo quantitative HDV RNA testing. We also provide an algorithm that describes CLDF recommendations on the screening, diagnosis, testing, and initial management of Hepatitis D infection.

Abstract Library

Unlocking Boundless Knowledge Through Abstracts

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The Cost-Effectiveness of Increasing Hepatitis Delta Testing for Individuals co-Infected with HBV and HIV in the Netherlands.

Marchena Shyevon (S);Toy Mehlika (M)

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Hepatitis virus-associated B cell non-Hodgkin's lymphoma involves dysregulated epigenetic and RNA-mediated regulatory gene expression and altered snoRNA transcription.

Henning Amanda N (AN);Budeebazar Myagmarjav (M);Boldbaatar Delgerbat (D);Yagaanbuyant Dahgwahdorj (D);Duger Davaadorj (D);Batsukh Khishigjargal (K);Muccilli Samantha (S);Pardoe Jordan (J);Perinet Lara (L);Conway Olivia (O);Owusu-Ansah Darryl (D);Robichaux Kobe (K);Baumann Ryan (R);Alter Harvey J (HJ);Dashdorj Naranjargal (N);De Giorgi Valeria (V)

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Long-Term Post-transplant Outcomes in Patients with Hepatitis D Virus Infection at a High-Volume Liver Transplant Center.

Keser Muhammed Furkan (MF);Keser Zeynep Busra (ZB);Yurdaydin Cihan (C);Yilmaz Sezai (S);Harputluoglu Murat (M)